About / Lab Staff
Rumyana Ivanova Dodova
Education:
2009~ PhD student in Department of Medical Chemistry and Biochemistry – Molecular Medicine Center, Medical University - Sofia
2008 MSc in Cell biology and Pathology - Sofia University St. Kliment Ohridski, Faculty of Biology
2006 Bachelor in Biology - Sofia University St. Kliment Ohridski, Faculty of Biology
1997 Bachelor in Nursing– Medical College Jordanka Filaretova, Sofia
Previous and Current Employment:
2007 – 2008 technician, Molecular Medicine Centre, Medical University, Sofia
1997 – 2007 nurse, Neurology Clinic, National Cardiology Hospital, Sofia.
Language proficiency:
English, Russian
Research interests:
Oncogenetics, Genetics of multifactorial disorders
Participation in research projects:
Principal Investigator
2012-20213 Analysis of big deletions, insertions and rearrangements in BRCA1 and BRCA2 genes in Bulgarian patients with triple negative breast cancer
2011-2012 Genetic analysis of mutations in exon 11 of BRCA2 gene in Bulgarian patients with hereditary breast cancer
2010-2011 Analysis of polymorphisms in low-penetrance genes associated with high risk of breast cancer
Co-Investigator
2011-2012 Follow up of circulating tumor cells (CTC) levels in patients with metastatic breast carcinoma - prognostic and predictive meaning
2011-2012 Analysis of mutations in BRCA1 gene in Bulgarian patients with triple negative breast cancer
2009-2012 National University Complex in Biomedical and Translational Research, infrastructural project
2009-2011 Clinical and molecular markers with predictive value for survival, quality of life and treatment response in high-grade gliomas
2010-2011 Enhancing the capacity of the cores Cell and Tissue Cultures, Microarray and Laser Microdissection in Molecular Medicine Center, MU - Sofia, infrastructural project.
Publications:
1. Lyubomir Dourmishev, MD, PhD, Zornitsa Kamenarska, PhD, Maria Hristova, MD,
Rumyana Dodova, MSc, Radka Kaneva, PhD, and Vanio Mitev, MD, PhD Association of TNF-a polymorphisms with adult dermatomyositis and systemic lupus erythematosus in Bulgarian patients The International Society of Dermatology, 2012 doi: 10.1111/j.1365-4632.2012.05522.x
2. Eeles RA, Kote-Jarai Z, Al Olama AA, Giles GG, Guy M, Severi G, Muir K, Hopper JL, Henderson BE, Haiman CA, Schleutker J, Hamdy FC, Neal DE, Donovan JL, Stanford JL, Ostrander EA, Ingles SA, John EM, Thibodeau SN, Schaid D, Park JY, Spurdle A, Clements J, Dickinson JL, Maier C, Vogel W, D?rk T, Rebbeck TR, Cooney KA, Cannon-Albright L, Chappuis PO, Hutter P, Zeegers M, Kaneva R, … Slavov C, Mitkova A, … Popov E, Kachakova D, Dodova R, Belcheva O, Nikolov M, Mitev V,… Identification of seven new prostate cancer susceptibility loci through a genome-wide association study. Nat Genet. 2009 Oct;41(10):1116-21.
Presentations:
1. Rumyana Dodova, Stefan Bozhanov, Ilia Nikolov, Zinaida Garanina, Atanaska Mitkova, Radka Kaneva, Vanio Mitev, Elena Georgieva PIK3CA mutation screening in Bulgarian breast cancer patients. International conference on Bioinformatics and Computational Biology, 20-21 September 2012, Varna Bulgaria
2. Rumyana Dododva, Daniela Dacheva, Aleksandrina Vlahova, Tihomir Dikov, Svetlana Christova, Spartak Valev, Margarita Taushanova, Constanta Timcheva, Radka Kaneva and Atanaska Mitkova Mutation screening of BRCA1 gene in Bulgarian breast cancer patients The 22nd Meeting of European Association for Cancer Research 7-10 July 2012, Barcelona, Spain.
3. Rumyana Dododva, Darina Kachakova, Aleksandrina Vlahova, Tihomir Dikov, Svetlana Christova, Spartak Valev, Margarita Taushanova, Constanta Timcheva, Vanio Mitev, Radka Kaneva and Atanaska Mitkova. Association of polymorphisms in low-penetrance genes with breast cancer risk in Bulgarian cohort of familial cases and controls. The European Human Genetics Conference, 22-26 June 2012, Nuremberg, Germany
4. Rumyana Dodova, Daniela Dancheva, Aleksandrina Vlahova, Tihomir Dikov, Svetlana Hristova, Spartak Valev, Constanta Timcheva, Vanio Mitev, Radka Kaneva, and Atanaska Mitkova. Large genomic aberrations in BRCA1 and BRCA2 genes in Bulgarian breast cancer patients. Poster presentation. The European Human Genetics Conference, 28-31 May 2011, Amsterdam, The Netherlands.
5. Rumyana Dodova, Atanaska Mitkova, Daniela Dacheva, Marija Caulevska, Aleksandrina Vlahova, Tihomir Dikov, Spartak Valev, Margarita Taushanova, Constanta Timcheva, Vanio Mitev, Radka Kaneva and Svetlana Christova. BRCA mutation screening in Bulgarian breast cancer patients. Poster presentation European Congress of Pathology (ECP) 27 August - 01 September 2011, Helsinki, Finland
6. Daniela Dacheva, Rumyana Dodova, Aleksandrina Vlahova, Tihomir Dikov, Svetlana Christova, Spartak Valev, Constanta Timcheva, Vanio Mitev, Radka Kaneva and Atanaska Mitkova. Mutation screening of BRCA2 exons 11 in Bulgarian breast cancer patients. Poster presentation. The European Human Genetics Conference, 28-31 May 2011, Amsterdam, The Netherlands.
7. Rumyana Dodova, Atanaska Mitkova, Mariya Caulevska, Aleksandrina Vlahova, Tihomir Dikov, Theophil Sedloev, Atanas Jonkov, Svetlana Christova, Vanio Mitev and Radka Kaneva, Association of polymorphisms in BRCA1 gene with breast cancer risk in Bulgarian familial cases. The 21st Meeting of European Association for Cancer Research 26-29 June 2010, Oslo, Norway.
8. Atanaska Mitkova, Rumyana Dodova, Mariya Caulevska, Aleksandrina Vlahova, Tihomir Dikov, Theophil Sedloev, Atanas Jonkov, Ivo Kremensky, Svetlana Christova, Vanio Mitev and Radka Kaneva. Mutation screening of BRCA1 exons 2, 11, and 20 in Bulgarian breast cancer patients. European J. Human Genet. 2009
9. Dodova R, Mitkova A, Vlahova A, Dikov T, Sedloev T, Jonkov A, Kremensky I, Christova S, Mitev V and Kaneva R . Association of polymorphisms in BRCA1 exon 11 with breast cancer risk in Bulgaria. 8th Balkan Meeting on Human Genetics, Dubrovnik 2009
10. Atanaska Mitkova, Rumyana Dodova, Aleksandrina Vlahova, Tihomir Dikov, Theophil Sedloev, Atanas Jonkov, Ivo Kremensky, Svetlana Christova and Radka Kaneva, Mutation screening of BRCA1 exon 11 in Bulgarian breast cancer families – 20th Conference of European Association of Cancer Research, Lyon 5-8 July 2008.