About / Lab Staff


Reni Stoyova Tzveova

Education:

PhD student in Molecular Medicine Center, Sofia – 2011- current

Master’s Degree in Medical Chemistry - Sofia University “St. Kliment Ohridski”, Faculty of Chemistry and Pharmacy, Sofia, Bulgaria, 2012

Master’s Degree in Genetics- Sofia University “St. Kliment Ohridski”, Faculty of Biology, Sofia, Bulgaria, 2010

Bachelor’s Degree in olecular biology - Sofia University “St. Kliment Ohridski”, Faculty of Biology – 2006

Previous and Current Employment:

Sofia, Medical University, Medical Faculty, Department of Medical Chemistry and Biochemistry, PhD student, .03.2011 - current

Language proficiency:

English, Russian

Research interests:

Pharmacogenetics and genomics, Genetics of multifactorial diseases, Genetics of cardiovascular diseases, Inherited disorders and predisposition, Neurodegenerative disorders, Oncogenetics, Gene expression in cancer, Medical chemistry

Participation in research projects:

Principal Investigator

2012-2013 "Influence of genetic factors on indirect anticoagulant therapy in Bulgarian patients with cardiovascular disease". Principle investigator: Reni Tzveova, Medical University – Sofia

Co-Investigator

2012-2013 "Analysis of genetic polymorphisms in genes for plasminogen activator (PAI I) and Apolipoprotein E in patients with acute coronary syndrome" Principle investigator:: Prof. Dr. M. Lackova, Medical University – Pleven

2011-2012 "Genetic markers for myocardial infarction in Pleven Region" Principle investigator:: Prof. Dr. M. Lackova, Medical University – Pleven

2011-2012 "Early cognitive impairment in patients with arterial hypertension" Principle investigator: Prof. K.Naydenov, Medical University – Sofia

2011-2012 "Genomic analysis of mutations in patients with congenital anomalies of the kidney and urinary tract (VABOS)" Director / Project Coordinator: Dr. A. Bueva, Department of Pediatric Nephrology and Dialysis, Medical University - Sofia

 

Publications:

1. Naydenova G, Tzveova R, Kaneva R, Tzekova M. Genetic polymorphisms in CYP2C8, CYP2C9, CYP2J2 and risk of coronary artery disease, Medinfo, 04/2012, Year XII

Presentations:

1. Reni Tzveova, Stoyan Bichev ,Petar Atanasov , Atanaska Mitkova, Svetoslav Andonov ,Radka Kaneva,Gencho Nachev, Vanio Mitev. Allelic and genotypic frequencies of CYP3A5, CYP2C19 and VKORC1 in Bulgarian population. The European Human Genetics Conference, 22-26 June 2012, Nuremberg, Germany.

2. Diana Pendicheva, Reni Tzveova, Antoaneta Pandurska, Variant in metabolic genes and their influence on the treatment with selective serotonine reuptake inhibitors. International scientific conference, Stara Zagora, 2012

3. M. Stefanova, S. Jordanov, R. Tzveova, G. Stancheva, A. Mitkova, I. Chalakov, R. Kaneva, V. Mitev and T. Goranova. The prevalence of microsatellite instability and loss of heterozygosity in Bulgarian patients with laryngeal carcinoma. The 2011 European Multidisciplinary Cancer Congress, 23-27 September 2011, Stockholm, Sweden. /Eur J Cancer, September 2011, Vol 47 (suppl 1), page S551, 8525/

4. G. Stancheva, R. Tzveova, S. Jordanov, A. Mitkova, I. Chalakov, R. Kaneva, V. Mitev and T. Goranova. Promoter hypermethylation of CDKN2A gene in Bulgarian patients with laryngeal squamous cell carcinoma. Poster presentation. The 4-th International Congress of Molecular Medicine, 27-30 June 2011, Istanbul, Turkey. /In vivo 25:560 (2011)/

5. R. Tzveova, G. Stancheva, S. Jordanov, A. Mitkova, I. Chalakov, R. Kaneva, V. Mitev and T. Goranova. Promoter hypermethylation of DNA repair genes in Bulgarian patients with laryngeal carcinoma. Poster presentation. The European Human Genetics Conference, 28-31 May 2011, Amsterdam, The Netherlands. /Eur J Hum Genet, 2011, 19 (suppl 2): 217, P06.