About us / Management
Prof. Radka Kaneva, PhD
E-mail: kaneva@mmcbg.org
Education:
2000 PhD in Molecular Biology - Sofia Medical University, Bulgaria
1989 MSc in Molecular Biology, Genetic and Cell Engineering - Biology Faculty, Sofia University St. Kliment Ohridski,
1988 Bachelor in Biotechnology - Biology Faculty, Sofia University St. Kliment Ohridski, Bulgaria
Previous and Current Employment
2012 - Associated Professor, Department of Medical Chemistry and Biochemistry, Medical University -Sofia
2010 - 2011 Chief Assistant Professor, Department of Medical Chemistry and Biochemistry, Medical University -Sofia
2009 Senior Assistant Professor, Department of Medical Chemistry and Biochemistry, Medical University -Sofia
2008 Assistant Professor, Department of Chemistry and Biochemistry, Medical University -Sofia
2005 - Executive manager - Molecular Medicine Center, Medical University – Sofia
1998 - 2008 Molecular Biologist, Laboratory of Molecular Pathology,
University Hospital of Obstetrics and Gynaecology, Sofia
1994 - 1997 Research Associate, Neuroscience and Behaviour Research foundation, Sofia
1992 - 1993 Research Assistant, Laboratory of Molecular Pathology, University Hospital of Obstetrics and Gynaecology, Sofia
1989 - 1991 Graduate Research Assistant, National Centre of Oncology, Medical Academy, Sofia.
Trainings and research fellowships
2003 - 2004 Humboldt Return Fellowship, Alexander von Humboldt Foundation
2001 - 2003 Humboldt PostDoctoral Research Fellow, Institute of Human Genetics, University of Bonn, Germany, Alexander von Humboldt Foundation
1998 French-American School of Neurobehavioural Genetics, University of Northern Colorado, USA
1993 -1994 Visiting Research Fellow, Department of Biochemistry, University of Oxford, UK, Open Society Foundation
1992 Human Genetics Summer Course, Leuven, Belgium
Scientific Awards
2008 Award Panacea of Medical University - Sofia for special contribution to teaching, research and expert activity in the professional biomedical field
Membership in Professional Societies
International Society of Psychiatric Genetics
European Society of Human Genetics
European Association for Cancer Research
Bulgarian Society of Biochemistry, Biophysics and Molecular Biology
Youth Union Molecular Genetics in Medicine
Teaching Experience
Lecturer in Biochemistry course for medical students, 2008 -
Lecturer in Diagnostics and prevention of inherited disorders. Molecular medicine course for undergraduate medical students
Lecturer in Molecular diagnostics of inherited disorders course in the master program for molecular biology students
Lecturer in course Introduction of Quality Assurance System In Preclinical Disciplines Teaching On Under- And Postgraduate Level Of Bulgarian Medical Universities Funded by the PHARE, TEMPUS
Lecturer in postgraduate course Psychiatric genetics, Department of Psychiatry, Medical University - Sofia
Promoter of 13 master students in Molecular Biology and Genetics
Scientific Consultant of 4 master students in Medical Informatics and Statistics, FMI, Sofia University St. Kl. Ohridski.
Scientific consultant of 5 PhD students in Molecular Biology and Genetics
Expert activities
National Contact Person, Programme IDEAS, 7FP of European Commission
Language proficiency
English, German, Russian
Research interests
Genetics of complex diseases, Neuropsychiatric and behavioral genetics, Oncogenetics, Ophthalmogenetics, Pharmacogenetics and genomics
Participation in Research projects:
Principal Investigator
2009 - 2010 Analysis of polymorphic variants in candidate genes associated with prostate cancer. Project 51/Contract 28/2009 Research Fund of Sofia Medical University,
2008 - 2009 Analysis of large genomic deletions, insertions and rearrangements in MLH1 and MSH2 gene in Bulgarian patients with CRC. Project 40/Contract 15/2008 Research Fund of Sofia Medical University,
2004 - 2008 National programme genomics: Genomics of retinitis pigmentosa, G-3-03/2004-2008, National Science Fund, Ministry of Education and Science
2003 - 2007 National programme genomics: Genomics of affective disorders G-2-03/2003-2007, National Science Fund, Ministry of Education and Science, Coordinator and PI
2004 - 2005 Fine mapping of 4p16 locus linked with a bipolar affective disorder in Bulgarian family, Research Fund of Sofia Medical University, L21/2004-2005
2001 - 2002 Linkage analysis on chromosome 21q22 in patients with Bipolar Affective Disorder in Bulgarian Families, Research Fund of Sofia Medical University 2001-2002
1995 - 1998 Interactions between genetic and psychosocial vulnerability factors in affective disorders, Ministry of Education and Science
Co-Principal Investigator
International
2009 - 2013 Varieties of Impulsivity in Opiate and Stimulant Users, NIDA, USA, R01 DA021421, PI Assist. Prof. J. Vassileva
2007 - 2010 Genetic and phenotype study of partial epilepsies in Gypsies, NHMRC, Australia, ID 458736, PI Prof. L. Kalaydjieva
2006 - 2011 Genetic Epidemiology of Heroin addiction in Bulgaria, NIDA, USA, R01 DA018823, PI Prof. Alexander Todorov, subaward WU-07-50
2005 - 2008 Enhancing the capacity of biomedical research in Bulgaria: Molecular Medicine Centre, FP6-LIFESCIHEALTH LSH-2004-3-3, SSA- Promotion of cooperation with Associated Candidate Countries (ACC)
2005 - 2008 Bipolar Disorder in a genetic isolate, NHMRC, Australia, PI Prof. L. Kalaydjieva
1997 - 2000 European Collaborative Study on Molecular Genetics in Affective Disorders (Genes in Affective Disorders), BIOMED2 program IC20-CT97-0018 European, Coordinator Prof. J.Mendlewicz
1995 - 1996 Morphometric and neural connectivity characteristics of fetal brains at genetic risk for bipolar disorder Stanley Research Foundation Award PI Prof. A. Jablensky
1991 - 1995 EC Concerted Action on Affective Disorders: interactions between genetic and psychosocial vulnerability factors BIOMED1 program of EC, INCO Copernicus, Coordinator Prof. J.Mendlewicz
1991 - 1994 Fetal Brain Development and Schizophrenia NIH Fogarty grant, University of Southern California, PI Prof. V. Mednick
National
2011-2012 Early cognitive disturbances in patients with arterial hypertension., MU-Sofia, Assoc Prof.K. Najdenov
2011-2012 Analysis of the mutations in BRCA1 gene in Bulgarian patients with triple negative breast cancer, MU-Sofia, Assoc Prof. S.Christova
2011-2012 Study of the role of genomic rearrangements, deletions and duplications for the pathology of congenital anomalies of the kidney and urinary tract (CAKUT). MU-Sofia, Assoc Prof. А. Boueva
2011-2012 Association study of candidate genes and phenotypes in bipolar affective disorder MU-Sofia, Prof. V.Milanova
2011-2012 Investigation of mutation in HFE gene in patients with chronic liver disorders with concurrent syndrome of iron overload, MU-Sofia, Prof. L. Vladimirova
2010-2011 Study of the molecular basis of congenital anomalies of the kidney and urinary tract (CAKUT) in Bulgaria. Role of Pax2 for the pathogenesis of CAKUT, MU-Sofia, A/Prof. Bueva
2010-2011 Investigation of the diagnostic specificity of promoter hypermethylation of biomarkers in urine, associated with prostate cancer in Bulgarian patients, MU-Sofia, Prof. Ch. Slavov
2009-2013 National University Complex in Biomedical and Translational Research, infrastructural project, National Science Fund, Ministry of Education and Science, Coordinator, Prof. V. Mitev
2009-2012 Contemporary approaches for unravelling the genetic basis of epilepsy National Science Fund, Ministry of Education and Science, PI Prof. A. Jordanova
2009-2012 Clinical and molecular markers with predictive value for survival, quality of life and treatment response in high-grade gliomas, National Science Fund, Ministry of Education and Science, PI A/Prof. N. Gabrovsky
2009-2012 Genome-wide screening for CNVs in Mental Retardation, National Science Fund, Ministry of Education and Science, PI Prof. V. Bojinova -Chamova
2009-2012 Study of the genetic variations, associated with increased risk and identification of diagnostics and prognostics markers for prostate cancer, National Science Fund, Ministry of Education and Science, PI Prof. Ch Slavov
2009-2010 Enhancing the capacity of the cores Cell and Tissue Cultures, Microarray and Laser Microdissection in Molecular Medicine Center, MU - Sofia, infrastructural project, 8I-2009, PI Prof. V. Mitev
2009-2010 Genetic, neuropsychological and vascular markers for early detection of Alzheimers Disease, MU - Sofia, PI Prof. L. Trajkov, 4C-2009
2009-2010 Study of candidate genes in linkage region for partial epilepsy, MU – Sofia, PI T. Goranova
2009-2010 Analysis of big deletions, insertions and rearrangements in BRCA1 and BRCA2, MU – Sofia, PI Assist Prof A. Mitkova
2009-2010 Molecular diagnostic of deafness, MU – Sofia, PI Prof. K. Kunev
2009-2010 Squamous cell carcinoma of the larynx and the hypopharynx. Genetic defects associated with carcinogenesis and biological behaviour of the tumor, MU – Sofia, PI A/Prof. I. Chalakov
2009-2010 Familial associative analysis of neurocognitive disorders and DISC1 gene in bipolar affective disorder patients. MU – Sofia, PI Prof. V. Milanova
2009-2010 Study of relationship between polymorphic variants in interleukin 10 (IL10) and the dermatomiositis origin in Bulgaria, MU – Sofia, PI A/Prof. L. Durmishev
2009-2010 Study of the role of hepatocyte nuclear factor 1-beta (HNF1b) for the development of congenital anomalies of the kidney and urinary tract
2008-2011 Molecular pathways involved in mamary gland cancer, National Science Fund, Ministry of Education and Science, PI Assoc. Prof. E Georgieva
2008-2010 Enhancing the capacity of the Molecular Medicine Center, Medical University-Sofia for functional genomic, proteomic and metabolomic research, D002-118/2008
2008-2009 Study of the role of the polymorphisms in tumor necrosis factor- alfa (TNF-α) for dermatomyositis pathology in Bulgaria, MU – Sofia, PI A/Prof. L. Durmishev
2008-2009 Influence of genetic variants in ABCA4 gene on development of age-related macula degeneration (ARMD) and assessment of the risk for disease on Bulgarian population, MU – Sofia, PI Prof. I. Kremensky
2007-2008 Researching of genetic markers for determinating possibility of development of aerobic and anaerobic quality in sportsman who have active competitive sporting activity, National Sport Academy, PI Assoc.Prof. P. Atanasov
2007-2008 Role of the podocin gene (NPHS2) mutations for the pathology of steroid-resistant nephrotic syndrome and microalbuminuria population risk in Bulgaria, MU – Sofia, PI Assist Prof. O. Beltcheva
2007-2008 Search for mutations in BRCA1 и BRCA2 genes related to breast and prostate cancer, Research Fund of Sofia Medical University, PI Dr.A.Mitkova, contract 27
2007-2008 Investigation of the role of GRM1 gene polymorphisms in the susceptibility to affective disorders and opioide addictions, Research Fund of Sofia Medical University, PI Prof. I. Kremensky, contract 28
2007-2008 Investigation of genetic characteristics, related to aerobic and anaerobic qualities, relevant to sport activities, National Sport Academy, PI, A/Prof. P. Atanasov
2007-2008 Endophenotype characteristics of Bipolar Affective Disorder patients, Research Fund of Sofia Medical University, PI Prof. V. Milanova, contract 45
2006-2008 Establishing a SNP genotyping and Gene Expression Core at Molecular Medicine Center, Medical University, Sofia, DRI-15, 2006, National Science Fund, Ministry of Education and Science, PI Prof.V.Ovcharov
2006-2007 Genetic polymorphisms in XRCC1 and XRCC3 genes related to the early radio-sensitivity reactions in endometrial and cervical cancer. Research Fund of Sofia Medical University, PI Dr A. Savov
2005-2008 Study of the molecular basis of the endometrial cancer in Bulgaria, National Science Fund, Ministry of Education and Science, Bulgaria,, PI Assoc. Prof. N. Doganov
2001-2002 Microsatellite instability analysis in Bulgarian patients with Colorectal Cancer, Research Fund of Sofia Medical University, PI Dr A. Savov
2001-2005 Investigation of the clinical and pathomorphological characteristics of the hereditary and sporadic colorectal cancer, National Science Fund, Ministry of Education and Science, PI Prof. D. Damyanov
1991-1994 Molecular Genetics of endogenous psychosis: Schizophrenia and bipolar affective disorder, Ministry of Education and Science, PI Prof. Jablensky
Consultant
2005-2007 Prevalence of primary aldosteronism in a selected hypertensive population, National Science Fund, Ministry of Education and Science Young Scientists Award, PI Dr. J. Matrozova
2005-2008 Study of the role of genetic polymorphisms of xenobiotic metabolism related enzymes and factors involved in the immune response for the tumor progression and prognosis in colorectal cancer, PI A/Prof. T.Vlaykova, TU-Stara Zagora, VU-L-05/2005, National Science Fund, Ministry of Education and Science
Publications in journals with peer review:
1. Kote-Jarai Z, Olama AA, Giles GG, Severi G, Schleutker J, Weischer M, Campa D,Riboli E, Key T, Gronberg H, Hunter DJ, Kraft P, Thun MJ, Ingles S, Chanock S, Albanes D, Hayes RB, Neal DE, Hamdy FC, Donovan JL, Pharoah P, Schumacher F, Henderson BE, Stanford JL, Ostrander EA, Sorensen KD, Dörk T, Andriole G, Dickinson JL, Cybulski C, Lubinski J, Spurdle A, Clements JA, Chambers S, Aitken J, Gardiner RA, Thibodeau SN, Schaid D, John EM, Maier C, Vogel W, Cooney KA,Park JY, Cannon-Albright L, Brenner H, Habuchi T, Zhang HW, Lu YJ, Kaneva R, Muir K, Benlloch S, Leongamornlert DA, Saunders EJ, Tymrakiewicz M, Mahmud N, Guy M, O`Brien LT, Wilkinson RA, Hall AL, Sawyer EJ, Dadaev T, Morrison J, Dearnaley DP, Horwich A, Huddart RA, Khoo VS, Parker CC, Van As N, Woodhouse CJ, Thompson A,Christmas T, Ogden C, Cooper CS, Lophatonanon A, Southey MC, Hopper JL, English DR, Wahlfors T, Tammela TL, Klarskov P, Nordestgaard BG, Røder MA, Tybjærg-Hansen A, Bojesen SE, Travis R, Canzian F, Kaaks R, Wiklund F, Aly M, Lindstrom S, Diver WR, Gapstur S, Stern MC, Corral R, Virtamo J, Cox A, Haiman CA, Le Marchand L, Fitzgerald L, Kolb S, Kwon EM, Karyadi DM, Orntoft TF, Borre M, Meyer A, Serth J, Yeager M, Berndt SI, Marthick JR, Patterson B, Wokolorczyk D, Batra J, Lose F, McDonnell SK, Joshi AD, Shahabi A, Rinckleb AE, Ray A, Sellers TA, Lin HY, Stephenson RA, Farnham J, Muller H, Rothenbacher D, Tsuchiya N, Narita S, Cao GW, Slavov C, Mitev V; The UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons` Section of Oncology; The UK ProtecT Study Collaborators, The Australian Prostate Cancer BioResource; The PRACTICAL Consortium, Easton DF, Eeles RA. Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study. Nat Genet. 2011 Jul 10. doi: 10.1038/ng.882. PubMed PMID: 21743467. IF 2010 (36.377)
2, Azmanov DN, Zhelyazkova S, Radionova M, Morar B, Angelicheva D, Zlatareva D, Kaneva R, Tournev I, Kalaydjieva L, Sander JW. Focal epilepsy of probable temporal lobe origin in a Gypsy family showing linkage to a novel locus on 7p21.3. Epilepsy Res. 2011 Jun 4. PubMed PMID: 21645995. IF 2010 (2.302)
3. Nikolov MA, Beltcheva O, Galabova A, Ljubenova A, Jankova E, Gergov G, Russev AA, Lynskey MT, Nelson EC, Nesheva E, Krasteva D, Lazarov P, Mitev VI, Kremensky IM, Kaneva RP, Todorov AA. No evidence of association between 118A>G OPRM1 polymorphism and heroin dependence in a large Bulgarian case-control sample. Drug Alcohol Depend. 2011 Aug 1;117(1):62-5. Epub 2011 Jan 31. PubMed PMID: 21277709 IF 2010 (3.365)
4. Azmanov DN, Dimitrova S, Florez L, Cherninkova S, Draganov D, Morar B, Saat R, Juan M, Arostegui JI, Ganguly S, Soodyall H, Chakrabarti S, Padh H, López-Nevot MA, Chernodrinska V, Anguelov B, Majumder P, Angelova L, Kaneva R, Mackey DA, Tournev I, Kalaydjieva L. LTBP2 and CYP1B1 mutations and associated ocular phenotypes in the Roma/Gypsy founder population. Eur J Hum Genet. 2011 Mar; 19(3):326-33. Epub 2010 Nov 17. PubMed PMID: 21081970; PubMed Central PMCID: IF 2010 (4.380)
5. Beltcheva O, Boueva A, Morgunova E, Boiadjieva E, Marinova S, Kaneva R and Mitev V. Novel mutation in Wilms tumour 1 gene associated with 6 steroid-resistant nephrotic syndrome, Nephrol Dial Transplant Plus, Volume 4 Issue 1 February 2011: 17-19. IF 2011(3.564)
6. Konstantinova D, Kaneva R, Dimitrov R, Savov A, Ivanov S, Dyankova T, Kremensky I, Mitev V. (2010) Rare mutations in the PIK3CA gene contribute to aggressive endometrial cancer. DNA Cell Biol. 2010 Feb;29(2):65-70. PubMed PMID: 19839777. IF 2009 (2.280)
7. Konstantinova D, Kadiyska T, Sokolova V, Kaneva R, Mirchev M, Savov A, Aleksandrova A, Nedin D, Kostadinov E, Damyanov D, Kremensky I, Mitev V. (2010) CHEK2 I157T and colorectal cancer in Bulgaria. J BUON. 2010 Apr-Jun;15(2):314-7. PubMed PMID: 20658728.
8. Azmanov DN, Dimitrova S, Florez L, Cherninkova S, Draganov D, Morar B, Saat R, Juan M, Arostegui JI, Ganguly S, Soodyall H, Chakrabarti S, Padh H, López-Nevot MA, Chernodrinska V, Anguelov B, Majumder P, Angelova L, Kaneva R, Mackey DA, Tournev I, Kalaydjieva L. (2010) LTBP2 and CYP1B1 mutations and associated ocular phenotypes in the Roma/Gypsy founder population. Eur J Hum Genet. 2010 Nov 17. PubMed PMID: 21081970. IF 2009 ( 3.564)
9. Konstantinova DV, Kadiyska TK, Kaneva RP, Tosheva EG, Guseva VT, Dimitrov BH, Dimitrov RG, Doganov NI, Ivanov SI, Kremensky IM, Mitev VI. (2010) CHEK2 I157T and endometrial cancer. DNA Cell Biol. 2009 Jan;28(1):9-12. PubMed PMID: 18834326. IF 2009 (2.280)
10. Eeles RA, Kote-Jarai Z, Al Olama AA, Giles GG, Guy M, Severi G, Muir K, Hopper JL, Henderson BE, Haiman CA, Schleutker J, Hamdy FC, Neal DE, Donovan JL, Stanford JL, Ostrander EA, Ingles SA, John EM, Thibodeau SN, Schaid D, Park JY, Spurdle A, Clements J, Dickinson JL, Maier C, Vogel W, Dörk T, Rebbeck TR, Cooney KA, Cannon-Albright L, Chappuis PO, Hutter P, Zeegers M, Kaneva R, … Slavov C, Mitkova A, ….. The UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons Section of Oncology, The UK ProtecT Study Collaborators, The PRACTICAL Consortium, Easton DF (2009) Identification of seven new prostate cancer susceptibility loci through a genome-wide association study. Nat Genet 41(10):1116-21. IF 2009 (34.284)
11. Angelicheva D, Tournev I, Guergueltcheva V, Mihaylova V, Azmanov DN, Morar B, Radionova M, Smith SJ, Zlatareva D, Stevens JM, Kaneva R, Bojinova V, Carter K,Brown M, Jablensky A, Kalaydjieva L, Sander JW. (2009) Partial epilepsy syndrome in a Gypsy family linked to 5q31.3-q32. Epilepsia. 2009 Mar 21.
12. Hantke J, Chandler D, King R, Wanders RJ, Angelicheva D, Tournev I, McNamaraE, Kwa M, Guergueltcheva V, Kaneva R, Baas F, Kalaydjieva L. (2009) A mutation in an alternative untranslated exon of hexokinase 1 associated with Hereditary Motor and Sensory Neuropathy - Russe (HMSNR). Eur J Hum Genet. 2009 Jun 17. IF 2009
13. Kaneva R, Milanova V, Angelicheva D, MacGregor S, Kostov C, Vladimirova R, Aleksiev S, Ivanova M, Stoyanova V, Loh A, Hallmayer J, Kalaydjieva L and Jablensky A. (2008) Bipolar disorder in the Bulgarian Gypsies: genetic heterogeneity in a young founder population, Am J Med Genet, Neuropsych Genet, 2008 Apr 28. IF 2006 ( 4.463)
14. Sivadorai P, Cherninkova S, Bouwer S, Kamenarova K, Angelicheva D, Seeman P, Hollingsworth K, Mihaylova V, Oscar A, Dimitrova G, Kaneva R, Tournev I, Kalaydjieva L (2008) Genetic heterogeneity and minor CYP1B1 involvement in the molecular basis of primary congenital glaucoma in gypsies, Clin Genet. 2008 Jul;74(1):82-7. Epub 2008 Jun 5 IF2006 ( 3.14)
15. Massat I, Lerer B, Souery D, Blackwood D, Muir W, Kaneva R, Nothen MM, Oruc L, Papadimitriou GN, Dikeos D, Serretti A, Bellivier F, Golmard JL, Milanova V, Del-Favero J, Van Broeckhoven C, Mendlewicz J (2007) HTR2C (cys23ser) polymorphism influences early onset in bipolar patients in a large European multicenter association study. Mol Psychiatry. 2007 Sep;12(9):797-8 IF 2006 (11.804)
16. Abou Jamra R, Fuerst R, Kaneva R, Orozco Diaz G, Rivas F, Mayoral F, Gay E, Sans S, Gonzalez MJ, Gil S, Cabaleiro F, Del Rio F, Perez F, Haro J, Auburger G, Milanova V, Kostov C, Chorbov V, Stoyanova V, Nikolova-Hill A, Onchev G, Kremensky I, Jablensky A, Schulze TG, Propping P, Rietschel M, Nothen MM, Cichon S, Wienker TF, Schumacher J (2007) The First Genomewide Interaction and Locus-Heterogeneity Linkage Scan in Bipolar Affective Disorder: Strong Evidence of Epistatic Effects between Loci on Chromosomes 2q and 6q. Am J Hum Genet. 2007 Nov;81(5):974-86. IF 2006 (12.629)
17. Konstantinova DV, Kadiyska TK, Kaneva RP, Ivanov SI, Dimitrov RG, Dyankova TV, Meinhardt KP, Gulubova MV, Vlaykova TI, Doganov NI, Mitev VI, Kremensky IM. (2007) Microsatellite instability in Bulgarian patients with endometrial cancer. J BUON. 2007 Jan-Mar;12(1):85-9.
18. Kadiyska T, Yakulov T, Kaneva R, Nedin D, Alexandrova A, Gegova A, Savov A,Mitev V, Kremensky I. (2007)Vitamin D and estrogen receptor gene polymorphisms and the risk of colorectal cancer in Bulgaria. Int J Colorectal Dis. 2007 Apr;22(4):395-400. Epub 2006 Jun 21. IF 2006 (2.006)
19. Kadiyska TK, Kaneva RP, Nedin DG, Alexandrova AB, Gegova AT, Lalchev SG,Christova T, Mitev VI, Horst J, Bogdanova N, Kremensky IM (2006) Novel MLH1 frameshift mutation in an extended hereditary nonpolyposis colorectal cancer family. World J Gastroenterol. 2006 Dec 28;12(48):7848-51.
20. Kadiyska TP, Goranova TE, Dineva GK, Nedin DG, Alexandrova AB, Gegova AT, Kaneva RP, Damyanov DN, Kremensky IM and Mitev VI (2006) Molecular screening for hereditary nonpolyposis colorectal cancer in Bulgaria. Central European Journal of Medicine 2006 June, 1: 2: 128-135
21. Chakarova CF, Cherninkova S, Tournev I, Waseem N, Kaneva R, Jordanova A,Veraitch BK, Gill B, Colclough T, Nakova A, Oscar A, Mihaylova V, Nikolova-Hill A, Wright AF, Black GC, Ramsden S, Kremensky I, Bhattacharya SS.(2006) Molecular genetics of retinitis pigmentosa in two Romani (Gypsy) families.Mol Vis. 2006 Aug 11;12:909-14. IF 2006 (2.377)
22. Dikeos DG, Papadimitriou GN, Souery D, Del-Favero J, Massat I, Blackwood D,Cichon S, Daskalopoulou E, Ivezic S, Kaneva R, Karadima G, Lorenzi C, MilanovaV, Muir W, Nothen M, Oruc L, Rietschel M, Serretti A, Van Broeckhoven C, Soldatos CR, Stefanis CN, Mendlewicz J. (2006) Lack of genetic association between the phospholipase A2 gene and bipolar mood disorder in a European multicentre case-control study. Psychiatr Genet. 2006 Aug; 16(4):169-71. IF 2006 (2.141)
23. Schumacher J, Kaneva R, Jamra RA, Diaz GO, Ohlraun S, Milanova V, Lee YA,Rivas F, Mayoral F, Fuerst R, Flaquer A, Windemuth C, Gay E, Sanz S, Gonzalez MJ, Gil S, Cabaleiro F, del Rio F, Perez F, Haro J, Kostov C, Chorbov V,Nikolova-Hill A, Stoyanova V, Onchev G, Kremensky I, Strauch K, Schulze TG,Nurnberg P, Gaebel W, Klimke A, Auburger G, Wienker TF, Kalaydjieva L, Propping P, Cichon S, Jablensky A, Rietschel M, Nothen MM. (2005) Genomewide scan and fine-mapping linkage studies in four European samples with bipolar affective disorder suggest a new susceptibility locus on chromosome 1p35-p36 and provides further evidence of loci on chromosome 4q31 and 6q24.Am J Hum Genet. 2005 Dec;77(6):1102-11. IF 12.649
24. Massat I, Souery D, Del-Favero J, Nothen M, Blackwood D, Muir W, Kaneva R, Serretti A, Lorenzi C, Rietschel M, Milanova V, Papadimitriou GN, Dikeos D, Van Broekhoven C, Mendlewicz J.(2005) Association between COMT (Val158Met) functional polymorphism and early onset in patients with major depressive disorder in a European multicenter genetic association study. Mol Psychiatry. 2005 Jun; 10(6):598-605. IF (9.335),
25. Kaneva R, Chorbov V, Milanova, Kostov C, Nickolov K, Chakarova C, Stoyanova V, Nikolova-Hill A, Krastev S, Onchev G, Kremensky I, Kalaydjieva L, Jablensky A (2004) Linkage analysis in bipolar pedigrees adds support for a susceptibility locus on 21q22. Psychiatr Genet –2004, 2004, Jun;14(2):101-106 IF2004 (2.162),
26. Blairy S, Linotte S, Souery D, Papadimitriou GN, Dikeos D, Lerer B, Kaneva R, Milanova V, Serretti A, Macciardi F, Mendlewicz J. (2004) Social adjustment and self-esteem of bipolar patients: a multicentric study.J Affect Disord. 2004 Apr;79(1-3):97-103. IF 2004 (2.703),
27. Mendlewicz J, Massat I, Souery D, Del-Favero J, Oruc L, Nothen MM, Blackwood D, Muir W, Battersby S, Lerer B, Segman RH, Kaneva R, Serretti A, Lilli R, Lorenzi C, Jakovljevic M, Ivezic S, Rietschel M, Milanova V, Van Broeckhoven C. (2004) Serotonin transporter 5HTTLPR polymorphism and affective disorders: no evidence of association in a large European multicenter study. Eur J Hum Genet. 2004 May;12(5):377-82 IF 2004 (2.741),
28. Papadimitriou GN, Dikeos DG, Souery D, Del-Favero J, Massat I, Avramopoulos D, Blairy S, Cichon S, Ivezic S, Kaneva R, Karadima G, Lilli R, Milanova V, Nothen M, Oruc L, Rietschel M, Serretti A, Van Broeckhoven C, Stefanis CN, Mendlewicz J. (2003) Genetic association between the phospholipase A2 gene and unipolar affectivedisorder: a multicentre case-control study. Psychiatr Genet. 2003 Dec;13(4):211-20. IF 2003 (2.414),
29. Oswald P, Souery D, Massat I, Del-Favero J, Linotte S, Papadimitriou G, Dikeos D, Kaneva R, Milanova V, Oruc L, Ivezic S, Serretti A, Lilli R, Van Broeckhoven C, Mendlewicz J. (2003) Lack of association between the 5HT2A receptor polymorphism (T102C) and unipolar affective disorder in a multicentric European study. Eur Neuropsychopharmacol. 2003 Oct;13(5):365-8. IF2003 (2.437),
30. Kremensky I, Todorova A, Jordanova A, Savov A, Tournev I, Iankova S, Georgieva B, Zaharova B, Kaneva R, Petkova R, Andonova S, Ivanova M, Ivanova N, Rainova R and Kalaydjieva L. (2003) Spectrum of mutations of the most common genetic disorders in Bulgaria J.Q.L.R- E.C. Qua. L., 2003, March – April, 1(2):172-185.,
31. Tzancheva M, Kadiyska T, Gegova AT, Dineva GK, Kaneva RP, Savov A, Marinov M, Kadyan, Penchev P, Nedin S, Alexandrova A, Ilieva J, Damyanov D, Mitev V and Kremensky I. (2003) Microsatelite instability in patients with colorectal cancer: Clinicomorphological Parallels. Annuaire de l Universite de Sofia St.Kliment Ohridski 2003 95:151-158,
32. Kadiyska T., Tzancheva M, Nedin D, Alexandrova A, Marinov M, Kaneva R, Damyanov D, Mitev V and Kremenski I (2003) MLH1 Promotor Hypermethylation in Bulgarian Patients with Colorectal Cancer, BJMG, 2003, 6: 3-8,
33. Massat I, Souery D, Del-Favero J, Van Gestel S, Serretti A, Macciardi F, Smeraldi E, Kaneva R, Adolfsson R, Nylander PO, Blackwood D, Muir W, Papadimitriou GN, Dikeos D, Oruc L, Segman RH, Ivezic S, Aschauer H, Ackenheil M, Fuchshuber S, Dam H, Jakovljevic M, Peltonen L, Hilger C, Hentges F, Staner L, Milanova V, Jazin E, Lerer B, Van Broeckhoven C, Mendlewicz J. (2002): Positive association of dopamine D2 receptor polymorphism with bipolar affective disorder in a European multicenter association study of affective disorders. Am J Med Genet. 2002 Mar 8;114(2):177-85. IF2002 ( 2.378),
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