Research Groups

Genetics of other common diseases

The research teams are also involved in several research projects focusing on common and multifactorial disorders. These are:

Cardiovascular disorders



Renal disorders 



"Study of the role of genomic aberrations, deletions and duplications in the pathology of congenital anomalies of the kidney and urinary tract (CAKUT)", 2011-2012.

"Study of mutations in HFE gene in patients with chronic liver diseases with or without iron overload syndrome", 2011-2012.

"Early cognitive impairments in patients with arterial hypertonia", 2011-2012.

“Contemporary approach for diagnostics, frequency assessment and genotype-phenotype correlations in patients with gestational diabetes mellitus in Bulgarian population”, 2009-2011.

“Study of the role of hepatocyte nuclear factor 1-beta  (HNF1b) for developing of innate (inborn) anomalities of urinary system”, 2009-2010.

“Phenotypic characteristics of idetached population”, 2009-2010.  

“Influence of genetic variants in ABCA4 gene on development of  age-related macula degeneration (ARMD) and assessment of the risk for disease on Bulgarian population”, 2008-2009.

“Frequency and character of the mutations in gene WT1 in patients with steroid-resistant nephrotic syndrome”, 2008-2009.

“Role of mutations in the podocin gene (NPHS2) for pathology of steroid-resistant nephrotic syndrome and for microalbuminuria population risk   in ”, 2007-2008.

“Study of genetic polymorphisms  4G/5G in promoter regions of  PAI-1 gene and   PIA1/PIA2 from gene, coding  IIIa subunit of  IIb/IIIa glycoprotein receptor in patients with miocardial infarction and healthy controls in Bulgarian population”, 2006-2007.

“Frequency of primary  alosterism  between patients with proven hypertonia“, 2005-2006.

“Genomics of the retinal pigment degeneration. Genomic analysis and identification of the genes affected in Retinitis Pigmentoza in Bulgarian Roma population”, 2004-2008.

“Markers for the degree of progression of the atherosclerotic alterations in blood vessels. Applicability of serum and genetic markers for evaluation of the atherosclerotic alterations in blood vessels”, 2004-2007.